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screen-well epigenetics library (bml-2836-0100)  (Enzo Biochem)

 
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    Enzo Biochem screen-well epigenetics library (bml-2836-0100)
    Screen Well Epigenetics Library (Bml 2836 0100), supplied by Enzo Biochem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/screen-well%C2%AE+epigenetics+library/pmc09984174-330-8-12?v=Enzo+Biochem
    Average 90 stars, based on 1 article reviews
    screen-well epigenetics library (bml-2836-0100) - by Bioz Stars, 2026-07
    90/100 stars

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    Overview of the reporter system and screen data. ( A ) Heatmap of the chromatin landscape at the integration sites of the integrated pathway reporters (IPRs) in K562 clone #5 used in this study. Z -scores of 25 chromatin features are indicated for all 19 IPRs. Chromatin features are colored by their type, and IPRs are clustered into chromatin groups based on the chromatin features. IPRs in bold are the two example IPRs depicted in B. Adapted from . ( B ) Left panel: genomic locations of the IPRs, colored by their associated chromatin group. Right panel: indel frequency distributions (in the absence of drug treatment) of two representative IPRs, one in euchromatin (IPR5), and one in heterochromatin (IPR7). ( C ) Number of drugs per target group in the screen. HDAC = histone deacetylase, JAK = Janus kinase, AurK = aurora kinase, PARP = poly (ADP-ribose) polymerase, ERD = <t>epigenetic</t> reader domain, HMT = histone methyltransferase, PIM = proviral integration site for moloney murine leukemia virus kinase, HDM = histone demethylase, DNMT = DNA methyltransferase, HAT = histone acetyltransferase and HIF = hypoxia inducible factor. ( D ) Schematic overview of the experimental layout and the readouts of the drug screen.
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    Overview of the reporter system and screen data. ( A ) Heatmap of the chromatin landscape at the integration sites of the integrated pathway reporters (IPRs) in K562 clone #5 used in this study. Z -scores of 25 chromatin features are indicated for all 19 IPRs. Chromatin features are colored by their type, and IPRs are clustered into chromatin groups based on the chromatin features. IPRs in bold are the two example IPRs depicted in B. Adapted from . ( B ) Left panel: genomic locations of the IPRs, colored by their associated chromatin group. Right panel: indel frequency distributions (in the absence of drug treatment) of two representative IPRs, one in euchromatin (IPR5), and one in heterochromatin (IPR7). ( C ) Number of drugs per target group in the screen. HDAC = histone deacetylase, JAK = Janus kinase, AurK = aurora kinase, PARP = poly (ADP-ribose) polymerase, ERD = <t>epigenetic</t> reader domain, HMT = histone methyltransferase, PIM = proviral integration site for moloney murine leukemia virus kinase, HDM = histone demethylase, DNMT = DNA methyltransferase, HAT = histone acetyltransferase and HIF = hypoxia inducible factor. ( D ) Schematic overview of the experimental layout and the readouts of the drug screen.
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    Overview of the reporter system and screen data. ( A ) Heatmap of the chromatin landscape at the integration sites of the integrated pathway reporters (IPRs) in K562 clone #5 used in this study. Z -scores of 25 chromatin features are indicated for all 19 IPRs. Chromatin features are colored by their type, and IPRs are clustered into chromatin groups based on the chromatin features. IPRs in bold are the two example IPRs depicted in B. Adapted from . ( B ) Left panel: genomic locations of the IPRs, colored by their associated chromatin group. Right panel: indel frequency distributions (in the absence of drug treatment) of two representative IPRs, one in euchromatin (IPR5), and one in heterochromatin (IPR7). ( C ) Number of drugs per target group in the screen. HDAC = histone deacetylase, JAK = Janus kinase, AurK = aurora kinase, PARP = poly (ADP-ribose) polymerase, ERD = <t>epigenetic</t> reader domain, HMT = histone methyltransferase, PIM = proviral integration site for moloney murine leukemia virus kinase, HDM = histone demethylase, DNMT = DNA methyltransferase, HAT = histone acetyltransferase and HIF = hypoxia inducible factor. ( D ) Schematic overview of the experimental layout and the readouts of the drug screen.
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    96 well- epigenetics screening library  (Cayman Chemical)
    90
    Cayman Chemical 96 well- epigenetics screening library

    96 Well Epigenetics Screening Library, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Image Search Results


    Overview of the reporter system and screen data. ( A ) Heatmap of the chromatin landscape at the integration sites of the integrated pathway reporters (IPRs) in K562 clone #5 used in this study. Z -scores of 25 chromatin features are indicated for all 19 IPRs. Chromatin features are colored by their type, and IPRs are clustered into chromatin groups based on the chromatin features. IPRs in bold are the two example IPRs depicted in B. Adapted from . ( B ) Left panel: genomic locations of the IPRs, colored by their associated chromatin group. Right panel: indel frequency distributions (in the absence of drug treatment) of two representative IPRs, one in euchromatin (IPR5), and one in heterochromatin (IPR7). ( C ) Number of drugs per target group in the screen. HDAC = histone deacetylase, JAK = Janus kinase, AurK = aurora kinase, PARP = poly (ADP-ribose) polymerase, ERD = epigenetic reader domain, HMT = histone methyltransferase, PIM = proviral integration site for moloney murine leukemia virus kinase, HDM = histone demethylase, DNMT = DNA methyltransferase, HAT = histone acetyltransferase and HIF = hypoxia inducible factor. ( D ) Schematic overview of the experimental layout and the readouts of the drug screen.

    Journal: Nucleic Acids Research

    Article Title: Chromatin context-dependent effects of epigenetic drugs on CRISPR-Cas9 editing

    doi: 10.1093/nar/gkae570

    Figure Lengend Snippet: Overview of the reporter system and screen data. ( A ) Heatmap of the chromatin landscape at the integration sites of the integrated pathway reporters (IPRs) in K562 clone #5 used in this study. Z -scores of 25 chromatin features are indicated for all 19 IPRs. Chromatin features are colored by their type, and IPRs are clustered into chromatin groups based on the chromatin features. IPRs in bold are the two example IPRs depicted in B. Adapted from . ( B ) Left panel: genomic locations of the IPRs, colored by their associated chromatin group. Right panel: indel frequency distributions (in the absence of drug treatment) of two representative IPRs, one in euchromatin (IPR5), and one in heterochromatin (IPR7). ( C ) Number of drugs per target group in the screen. HDAC = histone deacetylase, JAK = Janus kinase, AurK = aurora kinase, PARP = poly (ADP-ribose) polymerase, ERD = epigenetic reader domain, HMT = histone methyltransferase, PIM = proviral integration site for moloney murine leukemia virus kinase, HDM = histone demethylase, DNMT = DNA methyltransferase, HAT = histone acetyltransferase and HIF = hypoxia inducible factor. ( D ) Schematic overview of the experimental layout and the readouts of the drug screen.

    Article Snippet: For the drug addition, we combined two 96-well epigenetic drug screening libraries from two commercially available libraries from Selleck Chemicals and Enzo Life Sciences (for list of drugs see ).

    Techniques: Histone Deacetylase Assay, Virus

    Journal: Cell Reports

    Article Title: Temporal dynamics of HCMV gene expression in lytic and latent infections

    doi: 10.1016/j.celrep.2022.110653

    Figure Lengend Snippet:

    Article Snippet: 96 well- Epigenetics Screening Library , Caymen Chemical , Item No. 11076.

    Techniques: Virus, Recombinant, cDNA Synthesis, SYBR Green Assay, Purification, Next-Generation Sequencing, Software